Precis This book is a treatise about the origin of cancers. I would like to convince readers that the basic tenets of the theory of a stem-cell origin of cancers also constitute a unified theory of cancer. Stem-cell origin of normal (and cancer) cells: Vitruvian version Every truth passes through three stages before it is recognized. In the first it is ridiculed, in the second, it is opposed, in the third, it is regarded as self-evident. - Arthur Schopenhauer v vi Preface Every person has a unique story to tell. My story is about cancer. Cancer touches the lives of countless people. Often enough, it leaves indelible tracks. Many lives have been lost; others are forever changed. For those who confront this deadly scourge, there is a sense of urgency, if not of desperation. For those who face im- nent death, life becomes even more precious and carries a special meaning. As an oncologist, I am touched daily by cancer. I feel its inception, evolution, and aft- math. It seems as though we are fighting an incessant war against cancer at the front line in the trenches. This is my story about cancer. Some people are terrific storytellers. Others have incredible tales to tell.
The story of the Scotch-Irish is one of progress from something near barbarism in 1600 to civilization, from ignorance to a passion for education, from backwardness in most fields to daring achievement, from static traditionalism to dynamic individualism -- and all of this in space of two centuries. Just as the uncouth barbarian Vikings became the civilized Scandinavians, the barbarian Achaeans the classical Greeks, the forlorn toilers of the Dark Ages the great French people, so did the Scots of their own later Middle Ages transform themselves into a nation whose philosophers, inventors, literary men, and manufacturers were the admiration of the world. The Scots who went across the channel to Northern Ireland to participate in the Plantation of Ulster from 1609 onward ran the gamut of character. They all went to look for a better life or to escape miserable conditions or for sheer excitement. Most intended, if Ulster proved hospitable, to live there permanently. They took their families with them, and they soon made Ulster flourish. It was their descendants who, in the following century, searched for a better life in New England. The New England Scotch-Irish tells their history from the perspective of the people who lived it. It describes in vivid detail the everyday struggles the Ulster immigrants endured and the characteristics that enabled them to thrive in an unfamiliar and often inhospitable landscape.
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